Introduction: Clinical manifestations of the infection by SARS-CoV-2 are less frequent and severe in children than in adults;however, recent publications suggest the possibility of a severe clinical scenario secondary to the infection by this coronavirus called multisystem inflammatory syndrome in children (MIS-C) This syndrome has a post-infection nature and its physiopathology is probably the result of an abnormally organized activation
of the immune system in a genetic context of predispostion, and actived by the particular biology of SARS-CoV-2 Objective: To describe the first Cuban case with criterion of multisystemic syndrome associated to COVID-19 Case presentation: 2 years old male patient, previously healthy, with clinical and laboratory evidences of microangiopathic anemia, systemic hyperinflammation and organs and systems´ multiple dysfunction, associated with serologic evidences of previous infection by SARS-CoV-2 Conclusions: The proper approach to cases as the above mentioned in this work requires to keep a high level of clinical alert, with a clear definition of suspicious cases, multidisciplinary participation and the early establishment of and adequate therapeutic strategy that will be significant in the reduction of systems and organs damage´s extension;as well as increasing the chance to improve the dysfunction © 2020, Editorial Ciencias Medicas All rights reserved
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