Health Research Methods (HRM), Health Sciences Building (HSB), Department of Clinical Epidemiology and Biostatistics, McMaster University, West Hamilton, ON, Canada; McMaster Transfusion Research Program, McMaster University, Faculty of Health Sciences, Department of Medicine, Hamilton, ON, Canada; Health Research Methods (HRM), Health Sciences Building (HSB), Department of Clinical Epidemiology and Biostatistics, McMaster University, West Hamilton, ON, Canada; Centre for Evidence-Based Chinese Medicine-Beijing, University of Chinese Medicine, Beijing, China; Faculty of Medicine, University of Oslo, Norway; Norwegian Knowledge Centre for the Health Services, Oslo, Norway; Department of Medicine, Innlandet Hospital Trust-division, Gjovik, Norway; Department of Medicine and Department of Pathology and Molecular Medicine, McMaster University Thrombosis and Atherosclerosis Research Institute (TaARI), McMaster University, West Hamilton, ON, Canada; Department of Medicine, University of Toronto, Toronto, ON, Canada; Department of Medicine and. Clinical Laboratories, University of Rochester Medical Center, Rochester, NY; and. Schwartz/Reisman Emergency Medicine Institute, Department of Family and Community Medicine University of Toronto, Toronto, ON, Canada. Centre for Evidence-Based Chinese Medicine-Beijing, University of Chinese Medicine, Beijing, China; Department of Medicine and. Health Research Methods (HRM), Health Sciences Building (HSB), Department of Clinical Epidemiology and Biostatistics, McMaster University, West Hamilton, ON, Canada;