Departments of Anaesthesia and Intensive Care, Western Health, Gordon Street, Footscray, Melbourne, Australia; Department of Intensive Care, Austin Hospital, Heidelberg, Melbourne, Australia; Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; Department of Intensive Care, The Alfred, Melbourne, Australia; St Vincent's University Hospital, Dublin, Ireland; Royal Brisbane and Women's Hospital, Brisbane, Australia; The University of Melbourne, Parkville, Melbourne, Australia; Division of Intensive Care, Department of Anesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital and Helsinki University, Helsinki, Finland.