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Autologous platelet rich fibrin in the treatment of 3-wall intrabony defects in aggressive periodontitis - a randomized controlled clinical trial

Department of Periodontics Government Dental College and Research Institute Fort, Bangalore, Karnataka, India. Department of Periodontics Government Dental College and Research Institute Fort, Bangalore, Karnataka, India. Department of Periodontics Government Dental College and Research Institute Fort, Bangalore, Karnataka, India. Department of Endodontics and Conservative Dentistry Government Dental College and Research Institute Fort, Bangalore, Karnataka, India. Department of Periodontics Government Dental College and Research Institute Fort, Bangalore, Karnataka, India. Department of Periodontics Government Dental College and Research Institute Fort, Bangalore, Karnataka, India. Department of Periodontics Government Dental College and Research Institute Fort, Bangalore, Karnataka, India. Department of Periodontics Government Dental College and Research Institute Fort, Bangalore, Karnataka, India.

Journal of Periodontology. 2017;:1-9.
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Abstract
BACKGROUND Platelet rich fibrin (PRF), has recently found its application in osseous regeneration. The aim of present study is to explore the efficacy of PRF in treatment of intrabony defects in aggressive periodontitis. MATERIAL AND METHODS 54 intrabony defects in 17 patients were treated either with autologous PRF with open flap debridement (OFD) or OFD alone. Clinical and radiological parameters such as probing depth (PD), clinical attachment level (CAL), intrabony defect depth and % defect change were recorded at baseline and 9 months postoperatively. RESULTS Mean PD reduction and mean CAL gain was significantly greater in PRF as compared to control group. Furthermore, significantly greater percentage of mean bone defect change was found in the PRF group. CONCLUSIONS Within the limit of the present study, there was greater greater bone fill at sites treated with PRF with conventional OFD than conventional OFD alone.
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Language : English
Credits : Bibliographic data from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine