Department of Paedodontics and Preventive Dentistry, Goa Dental College and Hospital, Bambolim, Goa, 403202, India. firstname.lastname@example.org. Department of Paedodontics and Preventive Dentistry, Goa Dental College and Hospital, Bambolim, Goa, 403202, India.
European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry. 2019
AIM: To assess the effectiveness of topically-administered haemocoagulase (batroxobin) (HC) following dental extractions in children. DESIGN Split-mouth design, where either HC (test) or Normal Saline (control) (NS) was administered to children (5-9 years) requiring bilateral extractions of primary molars. Participants were randomised to (i) extraction sequence; (ii) test-solution administered thereafter. OUTCOME MEASURE time taken (in seconds) for complete cessation of
bleeding. RESULTS Thirty participants completed the trial receiving HS (n = 30) and NS (n = 30). No adverse events were reported. Time to bleeding cessation was lower in HS group (82.5 +/- 13.99 s) than NS group (240.5 +/- 54.34 s). Difference between groups (paired t test) was statistically very highly significant (P = 0.000). CONCLUSION Topical HC produced significant reductions in time for haemostasis and was clinically effective in controlling haemorrhage from extraction wounds in children. HC may be favourably utilised by paediatric dentists, especially with pre-cooperative or special-healthcare-needs patients, improving patient care.