Haemostasis and analgesia with autologous platelet-rich plasma in tonsillectomy

Department of ENT,Sikkim Manipal Institute of Medical Sciences,Sikkim Manipal University,Gangtok,India. Department of ENT,Sri Rama Chandra Medical College,Chennai,India. Department of ENT,Mon District Hospital,Nagaland,India. Department of ENT,Regional Institute of Medical Sciences,Imphal,India. Department of ENT,Jawaharlal Nehru Institute of Medical Sciences,Imphal,India. Department of Immunohaematology and Blood Transfusion,Regional Institute of Medical Sciences,Imphal,India.

The Journal of laryngology and otology. 2019;:1-7
OBJECTIVE A single-centre, single-blinded prospective experimental study was conducted to determine the effectiveness of autologous platelet-rich plasma applied to the tonsillar bed post-operatively in reducing post-operative pain and haemorrhage. METHODS Platelet-rich plasma, prepared prior to surgery, was applied with calcium gluconate to one randomly chosen tonsillar fossa. Pain and haemorrhage were analysed, using a visual analogue scale and a pre-defined grading scale respectively, four times on the day of surgery at 2-hourly intervals, and thrice on the following day. RESULTS The pain score and haemorrhage grade on the test side were lower than on the control side. These findings were statistically significant. CONCLUSION This pilot study, conducted in India, revealed valid positive results for a promising new technology. The manual preparation of platelet-rich plasma could be automated in the future to allow a larger sample size.
Study details
Language : eng
Credits : Bibliographic data from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine