Non-clinical interventions to prevent postpartum haemorrhage and improve its management: A systematic review

Hospices Civils de Lyon, Hopital Femme - Mere-Enfant, F-69500, Bron, France; Univ. Lyon, University Claude Bernard Lyon 1, Health Services and Performance Research HESPER EA 7425, F-69008, Lyon, France. Electronic address: laurent.gaucher@chu-lyon.fr. Univ. Lyon, University Claude Bernard Lyon 1, Health Services and Performance Research HESPER EA 7425, F-69008, Lyon, France; Hospices Civils de Lyon, Pole de Sante Publique, F-69003, Lyon, France. Inserm U1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team, Centre for Epidemiology and Statistics Sorbonne Paris Cite, DHU Risks in pregnancy, F-75004, Paris, Descartes University, France. Hospices Civils de Lyon, Hopital Femme - Mere-Enfant, F-69500, Bron, France; Univ. Lyon, University Claude Bernard Lyon 1, Health Services and Performance Research HESPER EA 7425, F-69008, Lyon, France. Univ. Lyon, University Claude Bernard Lyon 1, Health Services and Performance Research HESPER EA 7425, F-69008, Lyon, France; Reseau perinatal Aurore, F-69004, Lyon, France.

European journal of obstetrics, gynecology, and reproductive biology. 2019;240:300-309
Abstract
Postpartum haemorrhages (PPHs) account for around 200 deaths per year in the developed regions of the world. However, the efficacy of pharmacological and clinical interventions to prevent or manage PPHs is well established. Our objective was to determine the effectiveness of non-clinical interventions targeting healthcare professionals, organisations or facilities in preventing PPH or improving its management. We conducted a systematic review using the PRISMA four-step model. The MEDLINE and Cochrane databases were searched up to March 2019. Inclusion criteria were interventional studies, published in English of French language, aiming to reduce PPH outcomes for women in hospitals, regardless of study design. The studies' methodological quality was assessed according to the Cochrane EPOC criteria. We found 32 studies that met the inclusion criteria. None met all the methodological quality criteria. Six types of non-clinical interventions were identified: guideline dissemination, audit with feedback, simulation, training, clinical pathway and multifaceted interventions. Eleven studies reported a significant reduction in PPH rates and/or its complications, five studies reported a significant increase and 16 studies no significant results. The heterogeneity of the studies prevents us from identifying an effective non-clinical intervention in reducing PPH rates.
Study details
Study Design : Systematic Review
Language : eng
Credits : Bibliographic data from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine