Department of Hematology and Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Radboud University Medical Center, Nijmegen, The Netherlands. Department of Hematology, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway. CSL Behring, Marburg, Germany. CSL Behring, King of Prussia, USA. Department of Laboratory Medicine, Hematology Laboratory, Radboud University Medical Center, Nijmegen, Netherlands. Enzyre, Novio Tech Campus, Nijmegen, The Netherlands.