Association of Blood Groups with the Severity and Outcome of COVID-19 Infection in Children

Department of Pediatric Medicine, The Children's Hospital and The Institute of Child Health, Lahore, Pakistan. Department of Pediatric Hematology, The Children's Hospital and The Institute of Child Health, Lahore, Pakistan. Department of Pediatric Cardiology, The Children's Hospital and The Institute of Child Health, Lahore, Pakistan.

Journal of the College of Physicians and Surgeons--Pakistan : Jcpsp. 2021;30(1):S57-s59
Abstract
The objective of this study was to find out the association of ABO blood groups with the severity and outcome of corona virus disease 2019 (COVID-19) in children. It included all laboratory-confirmed cases of COVID-19 and post-COVID multisystem inflammatory syndrome in children (MIS-C)/ Kawasaki disease (KD) like illness, admitted from March to September, 2020 to The Children's Hospital, Lahore. Out of 66 children, 45 (68.2%) were COVID-19 and 21 (31.8%) MIS-C/KD temporally associated with SARS-C0V-2. The mean age was 7.9 ± 4.2 years. Majority of children had mild to moderate illness 38 (57.6%), while 23 (34.8%) had severe or critical disease. Among all patients, 24 (36.4%) had some underlying comorbidity. Blood group A was significantly associated with severe and critical disease (p=0.030). COVID-19 in children had generally a good outcome, but children with blood group A were more susceptible to severe/critical disease. Key Words: Coronavirus disease 2019, ABO blood groups, Children, Severity, Outcome.
Study details
Language : eng
Credits : Bibliographic data from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine