Guys' and St Thomas' NHS Trust, London, UK. Department of Translational Medicine, Lund University, Malmö, Sweden. Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Malmö, Sweden. Haemostasis and Thrombosis Unit, Division of Haematology, Haemophilia Centre, dCliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium.