Efficacy of topical application of autologous platelet-rich plasma in adult tonsillectomy patients: a randomised control study
Tonsillectomy is a painful surgery performed in cases of recurrent tonsillitis. Application of platelet-rich plasma to diminish the pain and morbidity post-tonsillectomy is gaining importance. This study evaluated post-operative pain and morbidity after autologous platelet-rich plasma application on the tonsil beds during tonsillectomy.
METHOD:Participants were randomised into group 1 (n = 28, peri-operative platelet-rich plasma intervention) and group 2 (n = 28, control). Post-tonsillectomy, patients were assessed (day 0, 1, 2, 3, 7 and 14) for pain, healing and time taken to return to normal activity. Data were analysed by independent t-test and chi-square test with p ≤ 0.05 as the significance level.
RESULTS:A significant decrease in the mean pain score up to day 7 (p < 0.05) and tonsillar fossae healing on days 2 and 3 (p < 0.05) post-tonsillectomy was noted. The majority of the patients returned to their routine activities after a week post-tonsillectomy.
CONCLUSION:Platelet-rich plasma application was effective in accentuating healing and reducing post-tonsillectomy pain and morbidity.
KEYWORDS: | Pain; Palatine Tonsil; Platelet-Rich Plasma; Tonsillectomy; Visual Analog Scale |
---|---|
MESH HEADINGS: | Administration, Topical; Adolescent; Adult; Female; Humans; Male; Middle Aged; Pain, Postoperative; Platelet-Rich Plasma; Postoperative Care; Postoperative Complications; Single-Blind Method; Tonsillectomy; Tonsillitis; Young Adult |
Study Design: | Randomised Controlled Trial |
---|---|
Language: | eng |
Credits: | Bibliographic data from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine |