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Blood product transfusion and lung transplant outcomes: A systematic review

Division of Cardiothoracic Surgery, Duke University, Durham, California, USA. Division of Cardiothoracic Anesthesiology, Duke University, Durham, California, USA. Duke University, Medical Center Library, Durham, California, USA. Department of Pathology, Duke University, Durham, California, USA.

Clinical transplantation. 2021
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Abstract
The perioperative transfusion of blood products has long been linked to development of acute lung injury and associated with mortality across both medical and surgical patient populations. The need for blood product transfusion during and after lung transplantation is common and, in many instances, unavoidable. However, this practice may potentially be modifiable. In this systematic review, we explore and summarize what is known regarding the impact of blood product transfusion on outcomes following lung transplantation, highlighting the most recent work in this area. Overall, the majority of the literature consists of single center retrospective analyses or the work of multicenter working groups referencing the same database. In the end, there are a number of remaining questions regarding blood product transfusion and their downstream effects on graft function and survival. This article is protected by copyright. All rights reserved.
Study details
Study Design : Systematic Review
Language : eng
Credits : Bibliographic data from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine