Allogeneic Bone Application in Association with Platelet-Rich Plasma for Alveolar Bone Grafting of Cleft Palate Defects

Associate Professor of the Department of Periodontology - University of Tennessee Health Sciences College of Dentistry, Memphis, TN, USA. Department of Oral and Maxillofacial Surgery, Comprehensive Care Center for Cleft Lip and Palate (CCCLP) of Paraná, Federal University of Paraná, Paraná, Brazil. Professor of Periodontics of the Department of Stomatology of the University of Santa Catarina, Paraná, Brazil. Professor of Oral Pathology of the Department of Stomatology of the University of Santa Catarina, Paraná, Brazil. Private Practice, Curitiba, Paraná, Brazil.

Contemporary clinical dentistry. 2021;12(2):143-149
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AIM: The aim of this study is to compare allogeneic bone grafts associated with platelet-rich plasma (ALBGs-PRP) to autogenous bone grafts (ATBGs) for alveolar reconstructions in patients with cleft lip and palate (CLP). MATERIALS AND METHODS The Maxillofacial Surgery Service of the Comprehensive Care Center for CLP (CCCLP) in Curitiba (Paraná, Brazil). PATIENTS Thirty out of 46 patients with 8-12 years of age and pre- or trans-foramen unilateral clefts were operated by the same surgeon. Groups were selected randomly after coin-toss for the first surgery to be ALBG-PRP. INTERVENTIONS Pre- and post-surgery cleft defect severity was registered by a score system using superimposed digitalized peri-apical radiographs. The hypothesis indicated ABG-PRP to be similar to the ABG was proved. RESULTS There was no statistically significant difference (P < 0.05) in bone augmentation for the ABG-PRP group (79.88%) when compared to the ABG group (79.9%). CONCLUSION ABG-PRP is indicated as a successful treatment modality to reduce the need for additional donor sites and reduce morbidity and hospital stay.
Study details
Language : eng
Credits : Bibliographic data from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine