Back to Search Results

A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease

General Surgery, Nottingham University Hospitals NHS Trust, Nottingham, GBR. Surgery, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA. Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA. Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND. General Surgery and Orthopaedic Surgery, Cornerstone Regional Hospital, Edinburg, USA. General Surgery, Stony Brook Southampton Hospital, New York, USA. Surgery, LaSante Health Center, Brooklyn, USA. Medicine, Beni Suef University Faculty of Medicine, Beni Suef, EGY. Neurology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA. Surgery, Halifax Health Medical Center, Daytona Beach, USA. Surgery, Dr.Pinnamaneni Siddhartha Institute Of Medical Sciences And Research Foundation, Gannavaram, IND. General Surgery, Liaquat University of Medical and Health Sciences, Jamshoro, PAK. Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Cureus. 2021;13(8):e16831
Full text from:

Other resources

Abstract
Pilonidal sinus is an acquired condition caused by irritation to the hair follicles at the natal cleft, presenting with an abscess or chronic infection. It is prevalent in young adults affecting their productive lifestyle with morbidities. There are varieties of treatment options; however, there is no consensus yet for the ideal procedure. Less invasive procedures have evolved to replace the traditional surgical techniques, which cannot significantly reduce the risks of recurrence and wound complications despite extensive surgeries. We aimed to assess the effect of fibrin glue as a primary treatment after cleaning the sinus in pilonidal sinus disease. We searched for articles from PubMed®, Ovid MEDLINE®, Ovid EMBASE®, and Cochrane CENTRAL. Six studies that included 336 patients in total were analyzed. Fibrin glue treatment in these studies reported a quicker return to normal activities postoperatively, a low rate of infection, and an acceptable rate of recurrence. Thus, fibrin glue seems beneficial in the management of pilonidal disease. However, further high-quality studies are essential to support and confirm this evidence. Future research should also evaluate its cost and implications in the ambulatory service.
Study details
Study Design : Systematic Review
Language : eng
Credits : Bibliographic data from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine