Department of Medicine, McMaster University, Hamilton, ON, Canada. Department of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia. Department of Pharmacy, University of Oklahoma Medical Center, Oklahoma City, OK. Pulmonary, Critical Care, and Sleep Medicine Section, Department of Medicine, University of Oklahoma Health Science Center, Oklahoma City, OK. Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN. Vanderbilt Institute for Clinical and Translational Sciences, Vanderbilt University Medical Center, Nashville, TN. Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN. ICU, Caboolture and The Prince Charles Hospitals, Metro North Hospital and Health Service, Brisbane, QLD, Australia. Critical Care Division, The George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia. School of Medicine, University of Queensland, St Lucia, QLD, Australia. Department of Health Research Methods, Evidence and impact, McMaster University, Hamilton, ON, Canada.