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Efficacy of platelet-rich plasma in rotator cuff repair: systematic review and meta-analysis

Hospital General Universitario Valencia, Spain. Electronic address: cristinasanchezlosilla@gmail.com. Instituto Cugat, Barcelona, Spain; Fundación García-Cugat, Barcelona, Spain. Instituto Cugat, Barcelona, Spain; Mutualidad de Futbolistas, Federación Española de Fútbol - Delegación Cataluña, Barcelona, Spain; Fundación García-Cugat, Barcelona, Spain. Mutualidad de Futbolistas, Federación Española de Fútbol - Delegación Cataluña, Barcelona, Spain.

Revista espanola de cirugia ortopedica y traumatologia. 2023
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Abstract
BACKGROUND/OBJECTIVE To analyze the efficacy and safety after the application of platelet-rich-plasma (PRP) as an adjuvant in arthroscopic rotator cuff repairs. MATERIALS-METHODS A bibliographic search of the literature of prospective studies with level of evidence one or two was carried out from January 2004 to December 2021, including studies that compare the functional and re-tear results after arthroscopic cuff repair. rotator with or without PRP. RESULTS A total of 281 articles were identified, of which 14 met the inclusion criteria. The overall re-rupture rate was 24%. In the PRP group, a decrease in the re-rupture rate and better functional results were demonstrated, although these differences were not significant. CONCLUSIONS Adjuvant treatment with PRP has shown promising results, although there is not yet enough evidence to provide a clear advantage for routine use in clinical practice.
Study details
Study Design : Systematic Review
Language : eng spa
Credits : Bibliographic data from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine