Institute of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland. Institute of Heart Diseases, University Hospital, Wroclaw, Poland. Division of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, North Caroline and Duke Clinical Research Institute, Durham, North Carolina, USA. Department of Medicine, Duke University, Durham, North Carolina, USA; Duke Clinical Research Institute, Duke University, Durham, North Carolina, USA. Baylor Scott and White Research Institute, Dallas, Texas, USA; Department of Medicine, University of Mississippi, Jackson, Mississippi, USA. Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA. Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. CSL Vifor, Glattbrugg, Switzerland. American Regent, Inc., Shirley, New York, USA. University Medical Center Göttingen, Department of Medical Statistics and DZHK (German Center for Cardiovascular Research), partner site Göttingen, Göttingen, Germany. Department of Cardiology (CVK) of German Heart Center Charité; Institute of Health Center for Regenerative Therapies (BCRT), German Centre for Cardiovascular Research (DZHK) partner site Berlin, Charité Universitätsmedizin, Berlin, Germany.