Tranexamic acid in control of haemorrhage after dental extraction in haemophilia and Christmas disease
Br Med J. 1972 May 6;2(5809):311-3 doi: 10.1136/bmj.2.5809.311.
Abstract
In a double-blind trial tranexamic acid (AMCA, Cyclokapron), 1 g three times a day for five days, significantly reduced blood loss and transfusion requirements after dental extraction in patients with haemophilia and Christmas disease. No side effects were seen in either group of patients. Screening tests showed no toxic action of tranexamic acid on the liver, kidney, or heart.
Metadata
| MESH HEADINGS: | Adolescent; Adult; Aged; Antifibrinolytic Agents; Blood Sedimentation; Chromium Isotopes; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fibrinogen; Heart Function Tests; Hemophilia A; Hemophilia B; Humans; Kidney Function Tests; Liver Function Tests; Middle Aged; Oral Hemorrhage; Tooth Extraction; Urea |
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Study Details
| Study Design: | Randomised Controlled Trial |
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| Language: | English |
| Credits: | Bibliographic data from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine |