Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada; Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada; George & Fay Yee Center for Healthcare Innovation, University of Manitoba, Winnipeg, MB, Canada; Division of Critical Care Medicine, Department of Anesthesiology, Centre de recherche CHU du de QuÚbec (Enfant-JÚsus Hospital), Axe SantÚ des populations et pratiques optimales en santÚ, UniversitÚ Laval, Quebec City, QC, Canada; Division of Critical Care, Department of Medicine, McMaster University, Hamilton, ON, Canada; Department of Internal Medicine, Section of Hematology & Medical Oncology, CancerCare Manitoba, Winnipeg, MB, Canada; Department of Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada