Population
Patients with idiopathic scoliosis undergoing correction surgery (n= 36).
Intervention
Tranexamic acid (TXA, n= 12).
Comparison
Epsilon amino caproic acid (EACA, n= 12). Placebo (saline, n= 12).
Outcome
Peri-operative blood loss was 50.1% lower in patients receiving TXA and 17.7% lower in patients receiving EACA compared with the placebo group. The volume of total packed red cell transfusion was 66.7% lower in patients receiving TXA and 45.6% lower in patients receiving EACA compared with placebo.