1.
Microangiopathic anemia and multisystem inflammatory syndrome associated to covid-19 in a cuban pediatric patient
Albelo, A. L. N., González, L. R. L., Pacheco, B. L. C., Cardellá, V. K., Hernández, J. M. H., Villafranca, R. C., Tallet, L. A. V., Días, A. B. P.
Revista Cubana de Pediatria. 2020;92:1-12
Abstract
Introduction: Clinical manifestations of the infection by SARS-CoV-2 are less frequent and severe in children than in adults;however, recent publications suggest the possibility of a severe clinical scenario secondary to the infection by this coronavirus called multisystem inflammatory syndrome in children (MIS-C) This syndrome has a post-infection nature and its physiopathology is probably the result of an abnormally organized activation of the immune system in a genetic context of predispostion, and actived by the particular biology of SARS-CoV-2 Objective: To describe the first Cuban case with criterion of multisystemic syndrome associated to COVID-19 Case presentation: 2 years old male patient, previously healthy, with clinical and laboratory evidences of microangiopathic anemia, systemic hyperinflammation and organs and systems´ multiple dysfunction, associated with serologic evidences of previous infection by SARS-CoV-2 Conclusions: The proper approach to cases as the above mentioned in this work requires to keep a high level of clinical alert, with a clear definition of suspicious cases, multidisciplinary participation and the early establishment of and adequate therapeutic strategy that will be significant in the reduction of systems and organs damage´s extension;as well as increasing the chance to improve the dysfunction © 2020, Editorial Ciencias Medicas All rights reserved