Trauma patients (14 studies, n= 3201).
Implementation of a massive transfusion protocol (MTP) on the mortality of trauma patients.
There was a wide range of outcomes, patient populations, and process indicators utilised by the different authors. MTP significantly reduced the overall mortality for trauma patients. No significant reduction was seen in either the 24-hour mortality or the 30-day mortality. However, when mortality timing was unspecified, mortality was statistically reduced.