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Subject Area
Adverse Effects of Transfusion
Allergic Reactions
Febrile Non-Haemolytic Transfusion Reactions
Haemolytic Reactions
Iron Overload
Respiratory Complications
Transfusion Transmitted Infections
Uncommon Complications of Transfusion
Alternatives to Blood
Albumin
Antifibrinolytics
Autologous Transfusion and Cell Salvage
Drugs Stimulating Platelet Production
Gene Therapy
Management of Anaemia
Non-Drug Interventions
Other Drug Interventions
Recombinant Coagulation Factors
Red Cell Substitutes
1
Blood Components
Convalescent Plasma
Cryoprecipitate
Plasma/FFP
Platelet Related Components
Platelets
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Red Cells
White Cells/Granulocytes
Whole Blood
Clinical Practice
Assessment of Abnormal Haemostasis
Errors and Near Misses
Measuring Blood Loss
Transfusion Education
Transfusion Practice
Fractionated Blood Products
Activated Protein C
Albumin
Anti-D IG
Factor VIII
Factor XIII
Fibrinogen Concentrate
Hyperimmune Immunoglobulin
Immunoglobulin G and IVIG
Prothrombin Complex Concentrate
Therapeutic Apheresis
Leucopheresis
Photopheresis
Plasmapheresis
Plateletpheresis
Red Cell Exchange
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Neonates and Paediatrics
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'author:"Wang M"'
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Psychological intervention in children with transfusion-dependent β-thalassaemia
Wang M, Huang M, Hong Y
Vox sanguinis. 2021
Abstract
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Abstract
BACKGROUND AND OBJECTIVES
Transfusion-dependent β-thalassaemia can lead to severe psychological issues in paediatric and adolescent patients. However, the psychological interventions for these patients are limited in clinical practice. We aimed to investigate the impact of a 3-month psychological intervention on the quality of life (QOL) of children with β-thalassaemia (12-18 years old) who relied on blood transfusion in this study.
MATERIALS AND METHODS
In the current randomized controlled trial, a total of 143 paediatric or adolescent patients (12-18 years old) with transfusion-dependent β-thalassaemia were recruited. They were randomized into the control group (n = 71) who received standard physiological treatment and the intervention group (n = 72) who received a 3-month intervention in addition to standard physiological treatment. The effects of the interventions on the QOL and psychological outcomes of these participants were analysed.
RESULTS
The 3-month intervention significantly improved the scores of PedsQoL 4.0 Generic Core Scales of paediatric patients with transfusion-dependent β-thalassaemia. It also significantly improved the psychological status and alleviated the depression among children and adolescent patients by alleviating anhedonia, negative mood and negative self-esteem among them.
CONCLUSION
Psychological intervention has positive effects on the treatment for children with transfusion-dependent β-thalassaemia.
Ovid Technologies, Inc.
Wiley
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