Bleeding trauma patients receiving platelet transfusion (5 studies, n= 1,757).
Higher platelet-to-red blood cell (RBC) transfusion ratio.
Lower ratio of platelet-to-RBC.
A high platelet:RBC compared with a low platelet:RBC ratio significantly improved 24 hour mortality, and 30- day mortality. There was no difference between platelet:RBC ratio groups in thromboembolic events and organ failure. Correction of coagulopathy was reported in five studies, in which platelet dose had no impact on trauma-induced coagulopathy.