Patients admitted to intensive care unit with COVID-19 (18 studies).
Systematic review examining the haemostasis with a wide range of dynamic haemostasis assays including platelet aggregation, global whole blood coagulation, thrombin generation assays, and fibrinolysis assays.
The included studies revealed normal or slightly reduced primary haemostasis, prolonged clot initiation, but increased clot firmness. Thrombin generation assay parameters generally were equivalent to the control groups or within reference range. Fibrinolysis assays showed increased clot resistance. Only six studies related their findings to clinical outcome.